Jane Paine
- Christened: 17 Apr 1625, London, London, England
- Marriage (1): Rev. Thomas Mayhew about 1647 in Tisbury, Wiltshire, England
- Marriage (2): Richard Sarson about 1658 in , Dukes, Massachusetts, United States
- Died: 1647, Edgartown, Dukes, Massachusetts, United States at age 22
 General Notes:
1. History of Martha's Vineyard, by Banks, p. 301-2.
2. History of Tilton Family in America, by F T Tilton
3. IGI
4. AF
She was Thomas' step-sister.
Jane married Rev. Thomas Mayhew, son of Governor Thomas Mayhew and Anna Martha Parkhurst, about 1647 in Tisbury, Wiltshire, England. (Rev. Thomas Mayhew was born in 1620 in Tisbury, Wiltshire, England and died in 1657.)
Jane next married Richard Sarson about 1658 in , Dukes, Massachusetts, United States.
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